LymphedemaV1, Main, Exploration, bibRecord, 000E83

Lower limb lymphedema in lung adenocarcinoma: Two case reports

Identifieur interne : 000E83 ( Main/Exploration ); précédent : 000E82; suivant : 000E84

Lower limb lymphedema in lung adenocarcinoma: Two case reports

Auteurs : Misae Shinoda [Japon] ; Haruka Akutsu [Japon] ; Toshihiro Ohtani [Japon] ; Tomohiro Tamura [Japon] ; Hiroaki Satoh [Japon]

Source :

Molecular and Clinical Oncology [ 2049-9450 ] ; 2016.

RBID : PMC:5038511

Abstract

Breast and gynecological cancers and their treatment may cause lymphedema of the upper and lower extremities, respectively. We herein report the cases of two patients with lung adenocarcinoma who developed lymphedema of the lower extremities. One patient harbored an epidermal growth factor receptor mutation and the other patient harbored an anaplastic lymphoma kinase fusion gene. The patients had developed intra-abdominal lymph node metastases and received several lines of chemotherapy. In both patients, lymphedema in the lower extremities developed >30 months after the initiation of first-line chemotherapy. To the best of our knowledge, these are the first reported cases of lung cancer patients who developed lymphedema in the lower extremities. Although rarely, lymphedema of the lower extremities may develop long after successful therapy with molecular-targeted therapy in advanced lung adenocarcinoma patients with a specific genetic etiological background.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038511

DOI: 10.3892/mco.2016.988
PubMed: 27699046
PubMed Central: 5038511

Affiliations:

Japon

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Lower limb lymphedema in lung adenocarcinoma: Two case reports</title>
<author><name sortKey="Shinoda, Misae" sort="Shinoda, Misae" uniqKey="Shinoda M" first="Misae" last="Shinoda">Misae Shinoda</name>
<affiliation wicri:level="1"><nlm:aff id="af1-mco-0-0-988">Division of Nursing, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Division of Nursing, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015</wicri:regionArea>
<wicri:noRegion>Ibaraki 310-0015</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Akutsu, Haruka" sort="Akutsu, Haruka" uniqKey="Akutsu H" first="Haruka" last="Akutsu">Haruka Akutsu</name>
<affiliation wicri:level="1"><nlm:aff id="af1-mco-0-0-988">Division of Nursing, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Division of Nursing, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015</wicri:regionArea>
<wicri:noRegion>Ibaraki 310-0015</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ohtani, Toshihiro" sort="Ohtani, Toshihiro" uniqKey="Ohtani T" first="Toshihiro" last="Ohtani">Toshihiro Ohtani</name>
<affiliation wicri:level="1"><nlm:aff id="af2-mco-0-0-988">Division of Pharmacy, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Division of Pharmacy, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015</wicri:regionArea>
<wicri:noRegion>Ibaraki 310-0015</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tamura, Tomohiro" sort="Tamura, Tomohiro" uniqKey="Tamura T" first="Tomohiro" last="Tamura">Tomohiro Tamura</name>
<affiliation wicri:level="1"><nlm:aff id="af3-mco-0-0-988">Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015</wicri:regionArea>
<wicri:noRegion>Ibaraki 310-0015</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Satoh, Hiroaki" sort="Satoh, Hiroaki" uniqKey="Satoh H" first="Hiroaki" last="Satoh">Hiroaki Satoh</name>
<affiliation wicri:level="1"><nlm:aff id="af3-mco-0-0-988">Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015</wicri:regionArea>
<wicri:noRegion>Ibaraki 310-0015</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">27699046</idno>
<idno type="pmc">5038511</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038511</idno>
<idno type="RBID">PMC:5038511</idno>
<idno type="doi">10.3892/mco.2016.988</idno>
<date when="2016">2016</date>
<idno type="wicri:Area/Pmc/Corpus">003096</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003096</idno>
<idno type="wicri:Area/Pmc/Curation">003095</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">003095</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000827</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000827</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">000599</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000599</idno>
<idno type="wicri:Area/PubMed/Curation">000599</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000599</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000599</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000599</idno>
<idno type="wicri:Area/Ncbi/Merge">008862</idno>
<idno type="wicri:Area/Ncbi/Curation">008862</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">008862</idno>
<idno type="wicri:doubleKey">2049-9450:2016:Shinoda M:lower:limb:lymphedema</idno>
<idno type="wicri:Area/Main/Merge">000E84</idno>
<idno type="wicri:Area/Main/Curation">000E83</idno>
<idno type="wicri:Area/Main/Exploration">000E83</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Lower limb lymphedema in lung adenocarcinoma: Two case reports</title>
<author><name sortKey="Shinoda, Misae" sort="Shinoda, Misae" uniqKey="Shinoda M" first="Misae" last="Shinoda">Misae Shinoda</name>
<affiliation wicri:level="1"><nlm:aff id="af1-mco-0-0-988">Division of Nursing, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Division of Nursing, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015</wicri:regionArea>
<wicri:noRegion>Ibaraki 310-0015</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Akutsu, Haruka" sort="Akutsu, Haruka" uniqKey="Akutsu H" first="Haruka" last="Akutsu">Haruka Akutsu</name>
<affiliation wicri:level="1"><nlm:aff id="af1-mco-0-0-988">Division of Nursing, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Division of Nursing, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015</wicri:regionArea>
<wicri:noRegion>Ibaraki 310-0015</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ohtani, Toshihiro" sort="Ohtani, Toshihiro" uniqKey="Ohtani T" first="Toshihiro" last="Ohtani">Toshihiro Ohtani</name>
<affiliation wicri:level="1"><nlm:aff id="af2-mco-0-0-988">Division of Pharmacy, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Division of Pharmacy, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015</wicri:regionArea>
<wicri:noRegion>Ibaraki 310-0015</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tamura, Tomohiro" sort="Tamura, Tomohiro" uniqKey="Tamura T" first="Tomohiro" last="Tamura">Tomohiro Tamura</name>
<affiliation wicri:level="1"><nlm:aff id="af3-mco-0-0-988">Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015</wicri:regionArea>
<wicri:noRegion>Ibaraki 310-0015</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Satoh, Hiroaki" sort="Satoh, Hiroaki" uniqKey="Satoh H" first="Hiroaki" last="Satoh">Hiroaki Satoh</name>
<affiliation wicri:level="1"><nlm:aff id="af3-mco-0-0-988">Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015</wicri:regionArea>
<wicri:noRegion>Ibaraki 310-0015</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Molecular and Clinical Oncology</title>
<idno type="ISSN">2049-9450</idno>
<idno type="eISSN">2049-9469</idno>
<imprint><date when="2016">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Breast and gynecological cancers and their treatment may cause lymphedema of the upper and lower extremities, respectively. We herein report the cases of two patients with lung adenocarcinoma who developed lymphedema of the lower extremities. One patient harbored an epidermal growth factor receptor mutation and the other patient harbored an anaplastic lymphoma kinase fusion gene. The patients had developed intra-abdominal lymph node metastases and received several lines of chemotherapy. In both patients, lymphedema in the lower extremities developed >30 months after the initiation of first-line chemotherapy. To the best of our knowledge, these are the first reported cases of lung cancer patients who developed lymphedema in the lower extremities. Although rarely, lymphedema of the lower extremities may develop long after successful therapy with molecular-targeted therapy in advanced lung adenocarcinoma patients with a specific genetic etiological background.</p>
</div>
</front>
</TEI>
<affiliations><list><country><li>Japon</li>
</country>
</list>
<tree><country name="Japon"><noRegion><name sortKey="Shinoda, Misae" sort="Shinoda, Misae" uniqKey="Shinoda M" first="Misae" last="Shinoda">Misae Shinoda</name>
</noRegion>
<name sortKey="Akutsu, Haruka" sort="Akutsu, Haruka" uniqKey="Akutsu H" first="Haruka" last="Akutsu">Haruka Akutsu</name>
<name sortKey="Ohtani, Toshihiro" sort="Ohtani, Toshihiro" uniqKey="Ohtani T" first="Toshihiro" last="Ohtani">Toshihiro Ohtani</name>
<name sortKey="Satoh, Hiroaki" sort="Satoh, Hiroaki" uniqKey="Satoh H" first="Hiroaki" last="Satoh">Hiroaki Satoh</name>
<name sortKey="Tamura, Tomohiro" sort="Tamura, Tomohiro" uniqKey="Tamura T" first="Tomohiro" last="Tamura">Tomohiro Tamura</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000E83 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000E83 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     PMC:5038511
   |texte=   Lower limb lymphedema in lung adenocarcinoma: Two case reports
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:27699046" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a LymphedemaV1

This area was generated with Dilib version V0.6.31.
Data generation: Sat Nov 4 17:40:35 2017. Site generation: Tue Feb 13 16:42:16 2024

Serveur d'exploration sur le lymphœdème

Lower limb lymphedema in lung adenocarcinoma: Two case reports

Lower limb lymphedema in lung adenocarcinoma: Two case reports

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.